Mir-219-P2

MirGeneDB ID

Cpo-Mir-219-P2

Family name

MIR-219 (all species)

Species

Guinea pig (Cavia porcellus)

MiRBase ID

cpo-mir-219b

Paralogues

Cpo-Mir-219-P2-as Cpo-Mir-219-P3

Orthologues

Aae-Mir-219 Aca-Mir-219-P2 Aga-Mir-219 Agr-Mir-219 Ami-Mir-219-P2 Bfl-Mir-219 Bge-Mir-219 Bko-Mir-219 Bla-Mir-219 Bpl-Mir-219 Bta-Mir-219-P2 Bta-Mir-219-P2-as Cfa-Mir-219-P2 Cfa-Mir-219-P2-as Cin-Mir-219 Cja-Mir-219-P2 Cli-Mir-219-P2 Cmi-Mir-219-P2 Cpi-Mir-219-P2 Csc-Mir-219 Cte-Mir-219 Dan-Mir-219 Dgr-Mir-219 Dlo-Mir-219 Dma-Mir-219 Dme-Mir-219 Dmo-Mir-219 Dno-Mir-219-P2 Dno-Mir-219-P2-as Dpu-Mir-219 Dre-Mir-219-P2a Dre-Mir-219-P2b Dsi-Mir-219 Dya-Mir-219 Eba-Mir-219 Eca-Mir-219-P2 Egr-Mir-219 Esc-Mir-219 Ete-Mir-219-P2 Gga-Mir-219-P2 Gja-Mir-219-P2 Gmo-Mir-219-P2a Gpa-Mir-219 Gsa-Mir-219 Gsp-Mir-219 Hmi-Mir-219 Hru-Mir-219 Hsa-Mir-219-P2 Hsa-Mir-219-P2-as Isc-Mir-219 Laf-Mir-219-P2 Lan-Mir-219 Lch-Mir-219-P2 Llo-Mir-219 Loc-Mir-219-P2 Mal-Mir-219-P2a Mal-Mir-219-P2b Mdo-Mir-219-P2 Mgi-Mir-219 Mml-Mir-219-P2 Mml-Mir-219-P2-as Mmr-Mir-219-P2 Mmu-Mir-219-P2 Mmu-Mir-219-P2-as Mom-Mir-219 Mun-Mir-219-P2 Neu-Mir-219-P2 Oan-Mir-219-P2 Obi-Mir-219 Ocu-Mir-219-P2 Ocu-Mir-219-P2-as Ofu-Mir-219 Ovu-Mir-219 Pab-Mir-219-P2 Pab-Mir-219-P2-as Pau-Mir-219 Pbv-Mir-219-P2 Pca-Mir-219 Pcr-Mir-219 Pfl-Mir-219 Pma-Mir-219-o2 Pmi-Mir-219 Pve-Mir-219 Rno-Mir-219-P2 Rno-Mir-219-P2-as Rph-Mir-219 Sha-Mir-219-P2 Sko-Mir-219 Sma-Mir-219 Sne-Mir-219 Snu-Mir-219 Spt-Mir-219-P2 Spu-Mir-219 Sro-Mir-219 Sto-Mir-219-P2 Tca-Mir-219 Tgu-Mir-219-P2 Tni-Mir-219-P2a Tni-Mir-219-P2b Tur-Mir-219 War-Mir-219 Xbo-Mir-219 Xla-Mir-219-P2c Xla-Mir-219-P2d Xtr-Mir-219-P2

Node of Origin (locus)

Gnathostomata

Node of Origin (family)

Bilateria

Genome context
(cavPor3)

scaffold_27: 3805724-3805788 [+] UCSC

Clustered miRNAs
(< 50kb from Mir-219-P2)

Mir-219-P2-as scaffold_27: 3805722-3805786 [-] UCSC
Mir-219-P2 scaffold_27: 3805724-3805788 [+] UCSC

Seed

GAUUGUC

Precursor
(pre-Mir +30nt flank)

CCAGGGCCCUGAACUCAGGAGCUUCGCCACUGAUUGUCCAAACGCAAUUCUUGUACGAGUCUGCGGCCAACCGAGAAUUGUGGCUGGACAUCUGUGGUUGAGCCCCGGGUGCAACAGGGGCCAGG

Get precursor sequence

Structure

        10          20        30        40        50        60  
CCAGGGCCCUGAACUCA--| A    C     U   U     AA           UACGAGUC 
                   GG GCUU GCCAC GAU GUCCA  CGCAAUUCUUG        U
                   CC CGAG UGGUG CUA CAGGU  GUGUUAAGAGC        G
GGACCGGGGACAACGUGGG^ C    U     U   -     CG           CAACCGGC 
   120       110       100        90         80        70

Deep sequencing

Comment

The MIR-219 family shows substantial variation of arm-usage and is currently, across all species, considered a co-mature.

3' NTU

Motifs

CNNC at 3p(+17)

Tissue expression

Bl	Bl	Bl	Bl	Oo	Oo	Oo	Oo	To	Wh

Mature sequence

Cpo-Mir-219-P2_5p

mirBase accession

MIMAT0047128

Sequence

0- UGAUUGUCCAAACGCAAUUCUUG -23

Get sequence

Co-mature sequence

Cpo-Mir-219-P2_3p

mirBase accession

MIMAT0047129

Sequence

43- AGAAUUGUGGCUGGACAUCUGU -65

Get sequence