Let-7-P2a1a

MirGeneDB ID

Mal-Let-7-P2a1a

Family name

Species

MiRBase ID

Paralogues

Mal-Let-7-P1b1 Mal-Let-7-P1b2 Mal-Let-7-P1c2 Mal-Let-7-P1d1 Mal-Let-7-P1d2 Mal-Let-7-P2a2a Mal-Let-7-P2a2b Mal-Let-7-P2a3a Mal-Let-7-P2a3b Mal-Let-7-P2a4a Mal-Let-7-P2a4b Mal-Let-7-P2b1a Mal-Let-7-P2b2a Mal-Let-7-P2b2b Mal-Let-7-P2b3a Mal-Let-7-P2b4a Mal-Let-7-P2b4b Mal-Let-7-P2c2b Mal-Let-7-P2c3

Orthologues

Aae-Let-7 Aca-Let-7-P2a1 Aga-Let-7 Agr-Let-7 Ami-Let-7-P2a1 Bge-Let-7 Bko-Let-7 Bpl-Let-7 Bta-Let-7-P2a1 Cfa-Let-7-P2a1 Cja-Let-7-P2a1 Cli-Let-7-P2a1 Cmi-Let-7-P2a1 Cpi-Let-7-P2a1 Cpo-Let-7-P2a1 Cte-Let-7 Dan-Let-7 Dlo-Let-7 Dma-Let-7 Dme-Let-7 Dmo-Let-7 Dno-Let-7-P2a1 Dpu-Let-7 Dre-Let-7-P2a1a Dsi-Let-7 Dya-Let-7 Eba-Let-7 Eca-Let-7-P2a1 Egr-Let-7 Esc-Let-7 Ete-Let-7-P2a1 Gga-Let-7-P2a1 Gja-Let-7-P2a1 Gmo-Let-7-P2a1a Gpa-Let-7 Gsa-Let-7 Gsp-Let-7 Hme-Let-7 Hmi-Let-7 Hru-Let-7 Hsa-Let-7-P2a1 Isc-Let-7 Laf-Let-7-P2a1 Lan-Let-7 Lch-Let-7-P2a1 Lgi-Let-7 Lhy-Let-7 Llo-Let-7 Loc-Let-7-P2a1 Mdo-Let-7-P2a1 Mgi-Let-7 Mml-Let-7-P2a1 Mmr-Let-7-P2a1 Mmu-Let-7-P2a1 Mom-Let-7 Mun-Let-7-P2a1 Npo-Let-7 Oan-Let-7-P2a1 Obi-Let-7 Ocu-Let-7-P2a1 Ofu-Let-7 Ovu-Let-7 Pab-Let-7-P2a1 Pau-Let-7 Pbv-Let-7-P2a1 Pca-Let-7 Pcr-Let-7 Pdu-Let-7 Pfl-Let-7 Ple-Let-7 Pmi-Let-7 Pve-Let-7 Rno-Let-7-P2a1 Rph-Let-7 Sha-Let-7-P2a1 Sko-Let-7 Sma-Let-7 Sne-Let-7 Snu-Let-7 Spt-Let-7-P2a1 Spu-Let-7 Sro-Let-7 Sto-Let-7-P2a1 Tca-Let-7 Tgu-Let-7-P2a1 Tur-Let-7 War-Let-7 Xbo-Let-7 Xla-Let-7-P2a1c Xla-Let-7-P2a1d Xtr-Let-7-P2a1

Node of Origin (locus)

Clupeocephala

Node of Origin (family)

Bilateria

Genome context
(GCA_001952655.1_M_albus_1.0_genomic)

KV884891.1: 605434-605504 [-] UCSC Ensembl

Clustered miRNAs
(< 50kb from Let-7-P2a1a)

Let-7-P2b1a KV884891.1: 605228-605305 [-] UCSC Ensembl
Let-7-P2a1a KV884891.1: 605434-605504 [-] UCSC Ensembl

Seed

GAGGUAG

Precursor
(pre-Mir +30nt flank)

GGAGCAAACAGCUGUGUUUGCACUGUGGGCUGAGGUAGUAGGUUGUAUAGUUUUAGGGUCACACCCGCACAGGGAGAUAACUAUUCAACCUACUGUCUUUCUCAAAGUGUCAGUGCACGUCUCAGGUUUCC

Get precursor sequence

Structure

        10         20         30        40        50        60     
GGAGCAAACAGCUGUGU-   -|   G    CU   GU         U      UUAGGGUCACAC 
                  UUG CACU UGGG  GAG  AGUAGGUUG AUAGUU            C
                  GAC GUGA ACUC  UUC  UCAUCCAAC UAUCAA            C
CCUUUGGACUCUGCACGU   U^   A    U-   UG         U      UAGAGGGACACG 
 .       120       110       100         90        80        70

Deep sequencing

Comment

Although there is a templated T at the 3' end of the 3p arm, the post-transcriptional addition of a terminal 3' U is supported by the conservation of Let7-P2 processing.

3' NTU

Yes

Motifs

CNNC at 3p(+17)

Tissue expression

Fe	Fe	In	Ma	Ma

Mature sequence

Mal-Let-7-P2a1a_5p

mirBase accession

None

Sequence

0- UGAGGUAGUAGGUUGUAUAGUU -22

Get sequence

Star sequence

Mal-Let-7-P2a1a_3p*

mirBase accession

None

Sequence

50- CUAUUCAACCUACUGUCUUUC -71

Get sequence