Mir-219-P3

MirGeneDB ID

Mmu-Mir-219-P3

Family name

MIR-219 (all species)

Species

House mouse (Mus musculus)

MiRBase ID

mmu-mir-219a-1

Paralogues

Mmu-Mir-219-P2 Mmu-Mir-219-P2-as Mmu-Mir-219-P3-as

Orthologues

Aae-Mir-219 Aca-Mir-219-P3 Aga-Mir-219 Agr-Mir-219 Ami-Mir-219-P3 Bfl-Mir-219 Bge-Mir-219 Bko-Mir-219 Bla-Mir-219 Bpl-Mir-219 Bta-Mir-219-P3 Cfa-Mir-219-P3 Cin-Mir-219 Cja-Mir-219-P3 Cmi-Mir-219-P3 Cpi-Mir-219-P3 Cpo-Mir-219-P3 Csc-Mir-219 Cte-Mir-219 Dan-Mir-219 Dgr-Mir-219 Dlo-Mir-219 Dma-Mir-219 Dme-Mir-219 Dmo-Mir-219 Dno-Mir-219-P3 Dpu-Mir-219 Dre-Mir-219-P3a Dsi-Mir-219 Dya-Mir-219 Eba-Mir-219 Eca-Mir-219-P3 Egr-Mir-219 Esc-Mir-219 Ete-Mir-219-P3 Gja-Mir-219-P3 Gmo-Mir-219-P3a Gmo-Mir-219-P3b Gpa-Mir-219 Gsa-Mir-219 Gsp-Mir-219 Hmi-Mir-219 Hru-Mir-219 Hsa-Mir-219-P3 Isc-Mir-219 Laf-Mir-219-P3 Lan-Mir-219 Lch-Mir-219-P3 Llo-Mir-219 Mal-Mir-219-P3a Mal-Mir-219-P3b Mdo-Mir-219-P3 Mgi-Mir-219 Mml-Mir-219-P3 Mmr-Mir-219-P3 Mom-Mir-219 Mun-Mir-219-P3-v1 Neu-Mir-219-P3 Obi-Mir-219 Ocu-Mir-219-P3 Ofu-Mir-219 Ovu-Mir-219 Pab-Mir-219-P3 Pau-Mir-219 Pbv-Mir-219-P3 Pca-Mir-219 Pcr-Mir-219 Pfl-Mir-219 Pmi-Mir-219 Pve-Mir-219 Rno-Mir-219-P3 Rph-Mir-219 Sha-Mir-219-P3 Sko-Mir-219 Sma-Mir-219 Sne-Mir-219 Snu-Mir-219 Spt-Mir-219-P3 Spu-Mir-219 Sro-Mir-219 Sto-Mir-219-P3-v1 Tca-Mir-219 Tni-Mir-219-P3a Tni-Mir-219-P3b Tur-Mir-219 War-Mir-219 Xbo-Mir-219

Node of Origin (locus)

Gnathostomata

Node of Origin (family)

Bilateria

Genome context
(mm10)

chr17: 34025010-34025072 [-] UCSC Ensembl

Clustered miRNAs
(< 50kb from Mir-219-P3)

Mir-219-P3 chr17: 34025010-34025072 [-] UCSC Ensembl
Mir-219-P3-as chr17: 34025012-34025073 [+] UCSC Ensembl

Seed

GAUUGUC

Precursor
(pre-Mir +30nt flank)

GCUUCUCUCCCCGUCCCGGGCCGCGGCUCCUGAUUGUCCAAACGCAAUUCUCGAGUCUCUGGCUCCGGCCGAGAGUUGCGUCUGGACGUCCCGAGCCGCCGCCCCCAAACCUCGAGGGGGAGA

Get precursor sequence

Structure

        10          20        30        40        50        60 
GCUUCUCUCCCCGUCCC--|   C       CU   U     A            AGUCUCU 
                   GGGC GCGGCUC  GAU GUCCA ACGCAAUUCUCG       G
                   CCCG CGCCGAG  CUG CAGGU UGCGUUGAGAGC       G
AGAGGGGGAGCUCCAAACC^   C       CC   -     C            CGGCCUC 
 120       110       100        90         80        70

Deep sequencing

Comment

The MIR-219 family shows substantial variation of arm-usage and is currently, across all species, considered a co-mature.

3' NTU

Motifs

CNNC at 3p(+17)

Tissue expression

Br	Br	Ce	Ce	Em	Em	He	Ki	Li	Lu	Ov	Pa	Sk	Sp	Te

Mature sequence

Mmu-Mir-219-P3_5p

mirBase accession

MIMAT0000664

Sequence

0- UGAUUGUCCAAACGCAAUUCUCG -23

Get sequence

Proposed targets

microrna.org: MIMAT0000664
TargetScanVert: mmu-miR-219a-5p
miRDB: MIMAT0000664

Co-mature sequence

Mmu-Mir-219-P3_3p

mirBase accession

MIMAT0017055

Sequence

41- AGAGUUGCGUCUGGACGUCCCG -63

Get sequence

Proposed targets

TargetScanVert: mmu-miR-219a-1-3p
miRDB: MIMAT0017055