10 20 30 40 50 60
UUAUAAUUUAUCAUCAAGA- -| CCUUAU GUUGCAUAUUUGCA
CU UUGUAGAA GGCCGGAGGUGUAUGCU U
GG AGCAUUUUCCGGCCUUCACGUAUGA U
AUACUCUACGGUAAAAACUA U^ UUCGCU CGUAAAAAUACUAA
130 120 110 100 90 80 70
Deep sequencing
Comment
It is not clear either from phylogenetic or syntenic information how many Mir-92 genes were present in the last common ancestor of bilaterians and how the vertebrate Mir-92s relate to the invertebrate Mir-92s and thus these multiple paralogues in invertebrates are classified here as orphans pending additional data.